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I asked one of my PCa buddies, Mike R., to respond to your recent entry because of his obvious qualifications and inclination to help. His response appears below:
"Kevin, I've been on Lupron for 6 years so I'll give you my experiences of effects and side effects. I work hard to stay fit and eat a healthy diet, so that may be part of my equation here. Until, last December, when I had a nasty concussion while playing basketball (at age 71) I was in maybe the best shape of my life. Lupon alone worked for me for 2 1/2 years. Until then, it knocked my PSA down, kept it down, and helped keep my bone scans and injection CAT scans clean. Once my PSA started to rise we added Zytiga to the mix and it has kept my PSA at the .04 level since then. I have not gained weight, gotten depressed or confused. I have wondered at times if dementia is setting in but my wife says "No way, you're just getting old." One possible side effect was losing my ability to have an erection but I think that was pretty well shot after I had my prostate out and then had 40 radiation treatments. Please keep in mind that every case is different. I wish you the best of luck as you continue on this tricky prostate survivor journey."
Best wishes Don O.