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Re: Just a theoretical question - what will be the best for bone metastases?
More conjecture additions to this, add another to the list you started: Dasatinib (Sprycel) in phase II/III now, it does build bone density(already known about), is already approved by FDA use for Leukemia patients. The trials now are for PCa useage, so you might be able to get it now under off label use (insurance won't cover it) or maybe under compasionate useage guidelines (aka Dr. Mark Moyad approach for obtaining)
Maybe estrogenic drugs, Dr. Myers points out in PCRI 2011 video, that patients using such for like 18 months, have bone density of 20-30 year people (his words). Plus such estrogenics can kill some hrpca in patients, Journal of Urology Nov, 2003 article as one reference.