Prostate Cancer Survivors

 

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Gleason score-7, PI-RADS score-2

Has anyone had anything close to this experience: My PSA was 40, then 10 days later 31. Then I had a biopsy with 12 of 14 cores showing positive for cancer with perineural invasion and extra prostatic extension. Gleason score of 4+3/7. Then I had a bone scan which, thankfully was negative/no bone cancer seen. Then I had an MRI with:

"No visible suspicious lesion by MRI to correlate with the known
prostate cancer (according to a surgical pathology report from a
prostate biopsy dated 4/29/2021). No visible extracapsular
extension from an underlying mass."

Pi-RADS score: 2 (Clinically significant cancer is unlikely to be present)

I don't understand how 12 of 14 biopsy cores could show cancer but a subsequent MRI deems cancer unlikely to be present. Any explanation/theory/guidance would be appreciated.

P.S. I started on ADT hormone therapy a week ago--after the biopsy but before the MRI.

Thanks.

Rich K

Re: Gleason score-7, PI-RADS score-2

The MRI will not see low grade tumor. I also am a Gleason 6 with 3 cores out of 12 being positive but my MRI was clear. I am on Active Surveillance. PSA 9.8

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