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Re: Castion resistant advanced prostate cancer

It sounds like an exciting treatment, but killing all the types of cancer cells one might have is still going to require multi-modal methods:

"Up to a third of those men treated to date show progressive disease despite treatment. This is likely due to a variety of factors. One important factor is whether the tumour cells uniformly express a high density of the PSMA receptor."

"Heterogeneity of PSMA receptor activity within the tumour population may mean that some sites will not respond to treatment with 177Lu PSMA, which will manifest as disease progression, and a rising PSA."

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5355374/

Another good thing is that it should be approved very quickly as it involves a drug (now with 177Lutetium attached) that has already been used as a contrast enhancer.

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