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Jean; - Yes, I agree with Frank that the numbers are not good. Didn't understand here that he had a surgery first. One always hopes that sort of PSA spike is from some other source - and anything is possible but the odds don't sound good. His Gleason score would be helpful in determining the seriousness also. Seems like anything over 7 is quite serious, not meaning to understate the seriousness of 7 and below but 8's and 9's are not good. Jon.
It's too bad his doc didn't inform him of the new molecular scans like C-11 choline, c-11 acetate, or PSMA. This scan would detect prostate cancer anywhere in his body. The radiation oncologist could then radiate any lesion that that was detected with this scan. He still may be able to do this, so he might want to look into this option.
Jean, I just want to add that all the advice given above is spot on and to add the thought that I think I'm the only man on this site who started out with Gleason 9 and a PSA of 62.3 and I'm still going strong after nine years, fully expecting to double that. So there is always hope. That coupled with a positive attitude and keeping fit should enable you friend's husband to follow my example. I hope so.