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PSA increase after brachytherapy

In June 2011 I had brachytherapy for 3 + 3 Gleeson prostate cancer. My PSA went down to 0.1 by 12/12. The it rose to 0.2 in 6/13 and dropped to 0.1 by 12/13. Then it started rising slowly: 0.3 in 12/14, 0.4 in 7/15. Then it shoot up to 1.5 by 7/16. What chance that I have full blown recurrence? Is there anyone with similar experience? What are my treatment options? I will seem Urologist on 8/10. I have already contacted my RO.

Re: PSA increase after brachytherapy

You might want to consider getting a 3T-MP-MRI. If suspicious spot is seen they could do a fusion biopsy. If confirmed PC then you could have focal treatment like, cryotherapy, focal laser ablation, HIFU....etc. I would favor HIFU...less likely to cause serious side effects.

You could also consider waiting till your PSA goes over 2 and get one of the new molecular scans. The C-11 acetate is probably the best one out there for recurrence inside the prostate.

Fred

Re: PSA increase after brachytherapy

M. Huq
Your RO may wish to eliminate prostatitis as a first step. If an infection does not exist the next best step in my layman's opinion would be to determine if and where the recurrence exists. I chose the PET-scan, and I am glad I did. The size and location of the "recurrence" helped determine my choice of treatments.
I fully documented my experience in an online journal which contains information you may find helpful in deciding what to do... and equally important what not to do; see: http://protondon.blogspot.com/
If you decide to take a look I suggest you begin with the entry titled "To My Family, Friends and Cyberspace Buddies." I will be available here to answer any questions that may occur to you.
Best wishes Don O.

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