Prostate Cancer Survivors






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Prostvac/clinical trial

I just wanted to let you know that there is a clinical trial phase 2 at NIH in Bethesda, Maryland that is still open, with a combination Prostvac (vaccine) with Enzalutamide or Enzalutamide alone. My husband entered the trial in June 2015 and so far we are very happy with it. It is for castrate resistant prostate cancer patients who have metastasized cancer, no or little pain, with a PSA>2, and who never had chemio. What we liked about this trial is that there is no placebo group. My husband was lucky to get in the arm with the PROSTVAC+ enzalutamide.
Since it is immunotherapy there is hardly any side effects, except the usual fatigue that also happens with Lupron (which he continues taking). The hardest part for us are the regular trips to Maryland (we live in California) and the stress associated with them.
His PSA, which was 5 went down to .04 and is now around .1. However, this could be due to the Enzalutamide alone and not to the vaccine. There is no way to know. My husband is feeling really well. He is sometimes emotional and has anxiety at times, but these symptoms are due mostly to the hormone treatment.
I will try to keep you updated on his progress.
Has anybody been on any of the PROSTVAC trials and what is your experience with them?