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I just got my blood test results back this morning and my PSA is up from 1.0 to 12.5 in two years. My primary doctor told me I need to see a Urologist immediately. I am 48yrs old and have been on HRT due to low testosterone. Needless to say I am having difficulty processing all of this. I thought I would drop a post here to get some advice from people with similar experiences.
Do not beat yourself up over the HRT. HRT does not increase PC risk. Actually there is a correlation between low T and prostate cancer. You may want to ask your Doc for a series of antibiotics to rule out prostatitis. You should get your % free PSA to help in the diagnosis.
Hockey your primary doctor's advice is very sensible and a urological consultation would be in your best interests. Hopefully prostatistis will be the culprit, but the dramatic PSA rise need's to investigated.
Fred's comments re HRT and PCa does reflect a changing medical view on causative factors re PCa. But having said that, we all know that androgen deprivation is very effective in treating diagnosed high grade gleason adenocarcinomas of the prostate. I can also recall several yana members from many years ago who chose to use testosterone after receiving treatment for PCa. One had a low grade tumour and the other high. Sadly both experienced aggressive recurrence.
I find your jump in PSA too alarming to waste time messing with antibiotics. I think you need to get another PSA, and if it confirms the rise, get a biopsy ASAP.