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Re: Do PSAs go up and down?

Here are a couple calculators where you can plug in your info - including free psa and get a percentage back. This is essentially what I was looking for. I am definitely in need of biopsies.

http://www.clevelandclinic.org/lp/prostate-cancer-risk-assessment/index.html

Kind of depressing but helpful in accepting reality. I have a 14-17% chance high risk cancer, 33-35% chance cancer. Biopsy on May 14th.

Another one with about the same results:
http://sunnybrook.ca/content/?page=occ-prostatecalc

Both sites come with the appropriate disclaimers

Re: Do PSAs go up and down?

Hope your May 14 biopsy went OK. You should have the results by now. Have had 4 of them over 7 years, so know the feeling. Very invasive to say the least. Was shocked when my initial biopsy delivered the diagnosis of PCa - Gleason 6(3+3). In my experience it is very important to get the actual written pathology report and study it well. Imperfect a measure, though it is, track your PSA.

In response to your question I regularly checked and tracked my PSA over 8 years. At the time of diagnosis it had risen to 3.2. After changing up a lot of stuff in my lifestyle, it got back down to as low as 1.8. Over time it spiked on a few occasions, as high as 6, but essentially rose over time, on average ever trending higher to recently 4-5 range, before I was driven to surgery by last biopsy results and progression in my case. I was kind of a nut about it and checked PSA on average every 6-8 weeks. This is a synopsis to date of my PCa and PSA history:

12/07 Age 57 - Diag PCa - PSA 3.2 - Bio 2/8 GS 6(3+3) - T1C
1/08 chg MD - begin WW/Expectant Management- Macrobiotic Vegan - BMI 26.1
9/08 PSA 1.7 - T1C - BMI 19.1
3/09 MRI - Inconclusive
6/09 PSA 1.8 - T1C - Bio 2/10 GS 6(3+3) - BMI 19.5
10/11 PSA 3.6 - T1C - Bio 3/9 GS 6(3+3)
3/15 PSA 4.9 - T1C - Bio 3/8 GS 7/3+4)
5/15 Age 65 - Rad Prost Surgery - GS 7(3+4) - No Lymph - 1 Positive Margin 2mm

Despite all my lifestyle efforts; macrobiotic diet, rigorous Yoga practice and supplements, seems genetics still trumps all. Jury is out for a couple of months before we check PSA following surgery. Being lean and well conditioned through Yoga ahead of surgery is helping to deliver a rapid recovery.

USA

Re: Do PSAs go up and down?

Yes my biopsy was ok - a couple HGPIN found - which may not mean anything according to recent studies. Continued testing is needed anyway with my PSA.

Re: Do PSAs go up and down?

Interesting
My psa started climbing in 2006 after I had a double bypass surgery. It started at 1.0 2006. 2.0 2007,1,75 2008, 2.75 2009, 3.0 2010, 4.0 2011 4.5 in 2012, 3.5 in 2013, 3.5 in 2014 now in 2015 its 8.0.

I had the regular psa done as well as the Free psa test. The free psa test indicated 8.0 with 15% free They said it means I have a 35% chance of having a positive biopsy result.

My question is does anyone know if Lipitor , lisinopril or Atenolol have any effect on creating a higher psa number? Urologist will do another psa later this month to see if psa changes. He did the DRE and there was no sign of any problems, I do not have any of the symptoms of BHP enlarged prostrate which normally is present.??

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