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You might also want to look up the drug under the name alpharadin which is the name used in the initial animal studies that show myelofibrosis, enlarged spleen, and increased intracranial hematopoiesis as outcomes. Jo
My husband became quite ill within one hour of his one and only dose. He'd been fully functioning and pain free for 7 years although his PCa was considered aggressive and he had wide spread bone mets. He had severe pain and nausea and lost 30 pounds in 3 weeks and became too weak to stand or sit up. With intensive physical therapy he was able to walk with arcane for very short distances until he relapsed again two months after the treatment. He developed a bleed in his small intestine and bladder infection and never recovered. He died on December 2nd from acute GI bleed and bronchopneumonia. Jo
