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I picked up this article which deals with the progression of Gleason grade/score for a tumor over time. What are your thoughts?
http://prostatecancerinfolink.net/2013/08/13/how-low-is-the-risk-for-gleason-score-progression-over-time/
I reviewed the article fairly quickly. My initial reaction is as follows:
1.Excellent article.
2.Stongly suggests Gleason scores are stable over time.
3.Double whammy for guys like me with an initial diagnosis of 4+3 (subsequently judged to be 4+4 after first-line treatment, same biopsy slide, different pathologist).
You did a great job locating information the two of us (and possibly many others) wondered about.
Best wishes Don O.
Don it was somewhat ironic that I read this study last week while I was in hospital after my recent procedure and just before I rerceived the pathology results.
When I was diagnosed back in 1996 I had four pathology labs examine my biopsy cores and got results oof 3+3=6, 2=3=5 and 3+4=7. My latst result seventeen years later was a surprising 5+4=9!
So....some tumours may well progress!! Full details to be published.
Exception to the rule? One wonders.*
All of us will be looking for the details Terry. To be published in your YANA story line?
Best wishes Don O.
* Are you tuned in Nellio?
I have read the latest comments regarding Gleason grade progression. The results of the Penney study and Terry's most recent biopsy would indicate that once again with PCa "There Are No Rules". This disease must be as extremely frustrating for researchers and clinicians, as it is for patients.
I would like to comment on having a MRI to find the location of your cancer. While a conventional MRI is not very good at seeing prostate cancer. A multi-modal MRI is very good at finding prostate cancer. Here is a link to a article that says the accuracy of detection cancer with a multi-modal MRI is more than 90%. http://www.umcn.nl/Zorg/Afdelingen/Radiologie/Documents/MRI%20in%20PCa%20PCRI%20Insights%20short%20(2).pdf