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Re: Genomic Health - Oncotype DX® Genomic Prostate Score (GPS

akai,

There was an entry onThe "New" Prostate Cancer Infolink at Oncotype DX prostate cancer test: ready for prime time? last September when the manufacturers had a media release announcing that they were ready to present a paper at the ASCO Genitourinary Cancers Symposium, being held this month in San Francisco. It seems that paper has not been presented yet, but there is another you might find of interest - Understanding new tests for risk of clinically significant prostate cancer.

As Mike Scott says in the second of these pieces Over the next few years we are going to see the development and marketing of a plethora of new tests related to the diagnosis and prognosis of prostate cancer. Some of these tests may have high utility and value. Others are likely to have a much lower value (but still see high use).

Since you seem to be very interested in all the new developments, may I suggest you check The "New" Prostate Cancer Infolink regularly. Mike Scott who collates the information and who makes the commentaries on the site is very knowledgeable and is often able to explain the potential value of new developments more clearly than some of the media releases, many of which tend to overstate this value.

Good luck
Terry in Australia

Re: Genomic Health - Oncotype DX® Genomic Prostate Score (GPS

Thanks Terry, I am checking out prostatecancerinfolink often now.

What do you think about Myraid Polaris test? Their claim is quite interesting, I will have to check and see if my insurance will pay for it.


Re: Genomic Health - Oncotype DX® Genomic Prostate Score (GPS

Mike Scott seems to be on top of Myraid Polaris - Prolaris: prognostically accurate but of limited utility?

In part he says:

In theory, these data suggest that the Prolaris test should be capable of discriminating between good and poor candidates for active surveillance. However, there may be a fly in the ointment. As yet we are not aware of any data showing that the Prolaris test can make accurate predictions based on tissue from an initial prostate biopsy, but such biopsy-derived tissue is what is available to the pathologist in the vast majority of cases prior to a decision whether to treat or to monitor individual patients. If the Prolaris test can only be used with accuracy on tissue available after a TURP or a radical prostatectomy, this will severely curtail the potential utility of this test.

I assume you aren't going to have surgery to get enough material for the test?

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