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Re: Diagnosed/ Need Help With findings

Well, I can't give you financial advice, but this excerpt from The Significance of Perineural Invasion Found on Needle Biopsy of the Prostate: Implications for Definitive Therapy may be of interest and some comfort with regard to perineural invasion:

The predictive value of PNI for extracapsular extension has decreased over time because of a downward stage migration driven largely by early detection efforts for prostate cancer. As patients have presented for definitive therapy with earlier, smaller tumors, the significance of PNI on prostate needle biopsy specimens has decreased. The presence of PNI on biopsy specimens does not preclude cure after definitive therapy or mandate wide excision of the ipsilateral neurovascular bundle at the time of surgery, and it should not deter the performance of radical prostatectomy in a patient who is otherwise a good surgical candidate.

Do a google search for prostate cancer perineural invasion and you can learn a deal more.

All the best
Terry

Re: Diagnosed/ Need Help With findings

2nd Pathology report. any comments appreciated as first consult with a radiology oncologist next week. I paid $150 for this 2nd report from a site recommended on this forum. Thanks for that Terry
For an additional $350 they offer a more detailed assessment but I passed on that


2ND OPINION RECEIVED 11/15/2012 MICROSCOPIC DESCRIPTION
A) Left Base: Benign prostatic glands and stroma.
B) Left Mid: Prostatic adenocarcinoma, Gleason score
3+3=6, measuring 2mm (10% of the tissue).
C) Left Apex: Prostatic adenocarcinoma, Gleason score
3+3=6, measuring 7mm (40% of the tissue).
D) Left Base Lat: Benign prostatic glands and stroma.
E) Left Lat Mid: Prostatic adenocarcinoma, Gleason score
3+3=6, measuring 2.5mm (20% of the tissue).
F) Left Lat Apex: Prostatic adenocarcinoma, Gleason score
3+3=6, measuring 1mm (7% of the tissue).
G) Right Base: Prostatic adenocarcinoma, Gleason score
3+4=7, measuring 4mm (30% of the tissue).
H) Right Mid: Small focus of atypical glands.
I) Right Apex: Prostatic adenocarcinoma, Gleason score
3+4=7, measuring 5mm (40% of the tissue).
J) Right Lat Base: Prostatic adencarcinoma, Gleason score
3+3=6, measuring 3mm (30% of the tissue).
K) Right Lat Mid: Small focus of atypical glands.
L) Right Lat Apex: Prostatic adenocarcinoma, Gleason
score 3+3=6, measuring 1mm (5% of the tissue).
Comments: Perineural invasion is seen in these biopsies.
Eight of twelve tissue cores are involved with
adenocarcinoma.
PHOTOMICROGRAPH
Malignant
Report Date: 11/16/2012
All malignant

Re: Diagnosed/ Need Help With findings

What other assessements were they offering? Ploidy analysis for example can be helpful in the deciosion making process.

Good to see that the 7b Gleason Scores have gone back a step.

Good luck

Terry in Australia

Re: Diagnosed/ Need Help With findings

For an additional $350 here is what they offer

http://theprostatelab.com/OURView.html

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