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You might like to mail Dr Fernando Premoli who has done a good deal of work on the subject at fernandopremoli@argentina.com He is very busy but I am sure if he has time he will respond.
The more surfing I do to learn about treatments, the more I get confused. Now I see that Dr. Myers, in his video of 9/7/2011, is very emphatic that transdermal estradiol is superior to DES. The video is located on page 5 of the following site. http://askdrmyers.wordpress.com/
