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I did 2 yrs. of ADT3 as neo-adj. drug therapy prior to specialized radiation (primary therapy), kind of like endorsed by Bolla Studies back in my 2002 diagnosis era. After 2 years on this it was getting old in dealing with the side effects and quality of life, and I had montly psa testings and had 8 very small rises consecutitively and saw if failing, so switched to DES and been using that over an 8 yr. period with successes and about no side effects and it assists bone density and memory (extra bonus).
I have a friend whom did ADT3 as his primary treatment in 1995-6 era and he has had 3 rebiopsies over the years, recently by color doppler ultrasound guided biopsies Dr. Lee did not find any PCa even in suspecious areas. He is not considered cured, but has done very well using the Leibowitz protocol (13 months on ADT3, then use only proscar for maintenance). Plus he can still do major treatments if and when he decides it necessary. This is a nice story, his psa originally was 11.0 and had 2 cores found positive, low gleason scores. His results are very noteworthy.
Note there is a new estradiol gel coming out that is custom compounded to the patients doseage level needed, this could likely in the future make patches obsolete because of there many issues in useage. This could be another therapy to consider either now or later.
I don't know if the following post covers old ground, but I see that Dr. Leibowitz has gone beyond the basic ADT3 protocol. I read about it at Compassionateoncology.com/publications. Scrolling down to "Dr. Bob's (not so) secret recipe for treating advanced or recurrent prostate cancer" one can read he now has a 3-pronged approach. I didn't read the paper carefully enough at this point to learn when he uses it, but it includes the basic ADT3 protocol, chemotherapy and an antiangiogenic cocktail, all of which he outlines in detail in the paper, published in 11/2008.
Yes Jack I was aware of his website and the multiple protocols he describes. I am searching for survivors who have personal experience/knowledge of Dr Bob and his group. Thanks for touching base old or new it makes no nevermind.