Prostate Cancer Survivors

 

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Re: PSA rising - testosterone or cancer

Here are my three thoughts, Steve:

1. Have all the tests been done by the same laboratory using the same manufacturer's test? There are more than 24 manufacturers and one of their results are precisely correlated.
2. No decision should EVER be contemplated or made based on a single unusual PSA test. It is not an accurate test and is subject to unexpainable variances.
3. You still have a prostate gland (or the remnants of one). That may be leaking PSA from any number of causes and is measurable now that yo are off ADT, which would have suppressed the PSA numbers.
4. You might like to read some of the problems with ULTRA SENSITIVE PSA

Just my thoughts. Good luck.

Terry in Australia

Re: PSA rising - testosterone or cancer

Thanks Terry.

Yes all tests from day one have been at the same lab...

It sounds like you are advising me to relax and see what we see in three months.

Fun to reach around the world to talk...

Steve in California

Re: PSA rising - testosterone or cancer

Diagnosed 2006 treatment and worries similiar to yours, I have now experienced 2 psa "bounces" since stopping Lupron which is not unheard of after brachytherapy. Statistics show that for some psa can continue to fluctuate for up to five years before reaching a nadir or constant level. The "bounces" also do not seem to corellate to treatment failure.
My testosterone level took over nine months to return to normal and during this time I experienced a significant psa bounce that went back down after a couple of months, about a year ago I had consecutive increases up to 0.43, but it went back down to 0.20.
Hope this helps - p (Alaska, USA)

Re: PSA rising - testosterone or cancer

Steve,
The Lupron was suppressing your psa well below natural levels and as it wears off it should settle into a range that is low and stable. You should expect psa after seeds and radiation to be in the .1 to .2 range, so you still have some increases ahead of you.

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