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Later used, HT option from 2000 Journal article & seen in 3 patients using it right now
I have to make this a short story and you can either try to read about such or look into it yourself. Anyway a Journal article was showing how patients whom are with PCa and already in HT type therapies and having psa rises on going, can try this combo and most likely will see psa drop or new response (how long????? would vary alot).
SCR is affected by androgens and antiandrogens (estrogens, and even tamoxifene). Now if you combine say casodex + estradiol (patches, or DES or emcyt) you will get a new response to your psa as to declining.
We have 3 guys in our prostate cancer support group doing this at about the same time, we all got psa declines that were worthy. Two of us using DES + casodex (generic) and the other guy with estradiol Mylan patches + casodex. All 3 of us a long term fighters in PCa and have used Lupron and or many other drugs along the way, so this is like later in the 'game' that these findings are happening. Someone else try it and go get a psa test to verify for yourself. We all got tested with a few weeks and then continued testings thereafter over a couple months time.
Re: Later used, HT option from 2000 Journal article & seen in 3 patients using it right now
Bob,
I realise that you wrote this in a hurry and you are trying to be helpful, but in reality most men who read this will nnot have any idea what you are talking about.
Can you re-visit and re-post so that it is more legible and understandable - and give the reference to the Journal entry to which you refer.
Re: Later used, HT option from 2000 Journal article & seen in 3 patients using it right now
Yes alot depends upon your own research or found informations and how you process alot of this new found info. Here is an example of what I am talking about in trials right now (using relaxifene and casodex, similar to tamoxifen and casodex and similar to casodex + estrogen in effectual useages).
Bicalutamide and Raloxifene in Treating Patients With Metastatic or Hormone-Refractory Prostate Cancer [Recruiting]
RATIONALE: Androgens can cause the growth of prostate cancer cells. Antihormone therapy, such as bicalutamide, may lessen the amount of androgens made by the body. Selective estrogen receptor modulators, such as raloxifene, may work together with bicalutamide to stop the growth of prostate cancer.
PURPOSE: This clinical trial studies giving bicalutamide and raloxifene together in treating patients with metastatic or hormone-refractory prostate cancer
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Ok link to another Journal piece on this subject matter, but not the 2000 Journal article, this is 2012 from Frontiers in Bioscience E4 and the link I found referencing this is:
www.ncbi.nlm.nih.gov/pubmed/21622172
If I get the other source we saw in a seminar, then I will post it herein, soon.
Re: Later used, HT option from 2000 Journal article & seen in 3 patients using it right now
For those of you confused a I am by these posts, Bob is talking about experimental treatments that he and some of the men in a similar position are doing because they believe that conventional therapies have failed to manage their disease.
Bob's story makes interesting reading and is at Robert Parsons He was diagnosed with a Gleason Score of 9, which, as you know is a huge warning sign, pointing to a very aggressive form of the disease. The fact tht he hits GOLD stauts next month, signalling twelve years since diagnosis says much about his determination to find a way to manage the disease.
