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There is a mathematical formula that relates psa to volume per cc of tumor by gleason grade. The lower the Gleason grade the higher the psa per cc of tumor volume. High grade PC gives off little psa per cc of tumor. It is used to estimate tumor volume if you know the psa and gleason grade. The formula used to be on the PCRI website under PC tools. Dr Bahn also uses this formula so he knows what to look for in terms of size and agressiveness when using CDU.
