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There was a study done with an internet link on it, from John Hopkins Hospital concerning using LHRH drugs like Lupron for longer useages, to supposedly help PCa morph into more viralent strains or aggression...was the message in that piece, they wrote. Sure makes everybody wonder about that. Similar talk has been said about using Avodart or proscar for longer terms. Plenty of controversy on PCa all over the place.
Dr. Barken coined the term micro mets years ago, it is PCa cells that cannot be detected by any scanning method available and could literally be in anyone with PCa. This explains recurrence or BCR failure in patients and especially guys who looked cured via surgery(or whatever) for 8-10 years and later found uncured because of such realities. Bottom line is they cannot disguish micro mets and there is no total definity in knowing if one has it, until plenty enough shows up for our less than perfect regular scanning methods. Some docs will openly admit this and plenty of them won't, of course they are selling a modality for ones possible cure. I still like total honesty and disclosures, even if it hurts to hear it.
You might want to google Bolla Abstracts Studies on PCa, it might be worth this patient to atleast know and analyze if he wishes to go that direction. I did with my case and had very lousy stats, so far approaching year 9 now without major problems...but could be on the cusp of the dragon. Some were thinking I had 2-3 years, glad that was wrong.
