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A Big Change

Lenny,

You're absolutely right that there ARE changes in attitude among many of the enlightened doctors, but interestingly, there was a report recently that implied that the number of men choosing AS was dropping, not increasing, despite the evidence accumulating regarding the prevlence of Low Risk or indolent disease.

One thing that DOES bother me a little is that where a Gleason 6 was clearly likely to be a Low Risk disease, the 'migration' of Gleason Scores, which started in 2005 is ikely to continue, so there will, over time be more an more men with graded higher Gleason Scores than they would have in the past, thus making them ineligible for AS.

In passing I wondered what change in a PSA level would trigger a saturation biopsy in your expert's protocol? Given the variances possible in PSA scores, I'd hope it was a very clear and continous increase that triggered this dratsic move.

All the best

Terry

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