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I'd guess the reference to pins and needles is because this might be a sign of pressure on his spinal column where compression often develops if the bone is damaged by the tumours.
Terry is correct. Any sign of numbness or pins & needles in the legs may be a sign of spinal cord compression. A possible effect of mets on the spine.
Please note "possible" and "may be".
Any such symptoms for those with confirmed spinal mets should refer to consultant without delay. This was emphasised to me at a talk on the subject by a specialist.
One can leave a trial at any time and revert to standard treatment. In this case I would only leave such a trial if absolutely certain that additional gains would be made.i.e. the Consultant is willing & agrees to add further treatments which might not be allowed on the trial.
