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Re: Things That Puzzle Me About PCa # 14 in an unlimited series

Well, Terry, more delicious food for thought.

As you are well aware, here in the good 'ol USA, we would have to work hard to see a medical oncologist who might suggest such a course of action/treatment. When I first was diagnosed, I read everywhere I looked that I should consult:
1. A urologist
2. A radiation oncologist
and
3. A medical oncologist...but probably this only after the disease had progressed so much that 1 & 2 could no longer play with it.

OK, I'm being a little facetious there, but really not that much. I doubt that many medical oncologists in the US even encounter many men with early PCa – the urologists/radiologists keep them in their corrals.

I am interested in what you think the implications for this are to Active Surveillance? If one subscribes to this opinion, is the early ADT attack necessary right away, or at what point does it become necessary? Roger from Indiana

Re: Things That Puzzle Me About PCa # 14 in an unlimited series

Terry,
I asked my onco about this very issue. He said that some do actually put this forward as a treatment strategy - but usually with older men. In my case, my relative youth would invite ADT resistance later on. He also mentioned that there's some evidence to suggest that long-term use of ADT (even on an intermittent basis) might encourage cells to become more aggressive (or perhaps he meant that it's the aggressive cells that survive.
Either way, the combination of age and aggressiveness, made me opt for radiation

Re: Things That Puzzle Me About PCa # 14 in an unlimited series

Terry,
Dr Bob Leibowitz in Los Angeles has been treating low risk patients with 13 months ADT3 for years and reports results equal to all other treatment options. He has published papers on his results that can be found on Compassionateoncology.com.

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