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psa going up

here is my story

feeling so down !

has anyone had the psa go up and then drop again

doctor visit tommarrow !

sugury 33 months ago
after the needle test it came back grade 4 gleason 8
fininding after the surgury
gleason score 7 involving 20 % of prostatic
tumor extend to margins bladder neck margin
venous absent
lymphatic absent
perineural present
seminal vesicle absent
lymph nodes negative for tumor

6 months after the sugury his psa 0.1
10 months 0.9
told to get radation
psa 6 months after radation psa 0.2
psa 12 months after 0.8
then at 18 months 1.9
at 24 months 3.8
NOW AT 27 months 7.5

Re: psa going up

Your timing is about right for what is termed a radiation 'bump' - where the PSA rises about 18 months to 2 years after the radiation therapy and then falls back. Very difficult to distinguish this from a genuine rise due to an aggressive disease.

Good luck with your appointment.

Terry in Australia

Re: psa going up

can you have a bump, after radation when you had the prosate removed
thanks sooooooooo much !

Re: psa going up

what's the timing? the farther apart, the more generally they rise---again, it is a generalization, not a data point or fact. i would seek other opinions, plural, especially an experienced surgeon at a place where they lots of pca.

Re: psa going up

William, why would you reccommend an apointment with a surgeon? What is required is an apointment with an oncologist, surely, who specialises in PCa.

Re: psa going up

here in the states, we need to have a quarterback, a team leader, otherwise, all the stuff gets dumped on the patient. historically, we have used the surgeon because all urologists are surgeons and clinicians, plus in a large hospital, they will consult the tumor board or work on a team that specializes with other members such as radiation, onocology, etc. on a specific area of cancer

Re: psa going up

And this is the main reason that the treatment of PC is so bad in the US. In every other cancer the oncologist is the team leader and directs the surgeon and radiologist. PC is the only cancer left that the surgeon is the team leader and as long as this continues there will be over treatment, missed diagosisis and bad clinical staging.

Re: psa going up

This pattern doesn't look like a radiation bump. It looks like a consistant rise after radiation with an excellerating psa doubling time. I would get a 2nd opinion from an oncologist.

Re: psa going up

I agree with Mr. Thompson as I am going through the same process as you have described. Have your urologist refer you to the staff oncologist to determine what options are available to you. After surgery, there is no PSA bump.

Good Luck, Jack

Re: psa going up say the doc !!!!!!!

i know will have to go on hormone thephy
lupron one month of pills
along with shoot 1/2 thru the pills
then after that shot another one
then psa reading again

what am i instore for with the hormone thing

thanks !

Re: psa going up say the doc !!!!!!!

Go along to HORMONE THERAPY and follow the links there.

Some men have very little troube in dealing with the side effects of Hormone therapy or ADT - others do. There is no way of predicting this.

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