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Many thanks for your replies. I guess unfortunately that Alan's cancer is a fast growing one. He had no symptoms it was just a chance psa test 12 months ago. A test that was requested by Alan 5 years and 3 years ago. His GP put him off by saying you have no symptoms and the test is inconclusive!! His GP can't do enough for him now. I wonder why? The Zoladex is working well. Last reading.03.