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To me, the meat of the article is:
"There is a real need to find a way of diagnosing the tigers, without finding the pussycats. Scans using diffusion-weighted magnetic resonance imaging (MRI) may have the potential to fulfill this need..."
I see the ability to reliably image small PCa tumors as about the highest priority task in the PCa world, but diffusion-weighted MRI may or may not fill the bill. If they could accurately and reliably image small PCa tumors, then they could: screen early, watch the tumors - and the first time one as much as twitched - freeze it or burn it with focal cryo or HIFU.
The current 12-needle transrectal biopsy is being used about like a trip wire by most urologist. Earlier or lower PSA screening mostly results in more men being diagnosed whom you don't know whether or not to treat. It would only make the strange land stranger, Stranger.
