Prostate Cancer Survivors

 

YANA - YOU ARE NOT ALONE NOW

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Re: Intermittent HT

Yes, I am - see my story. Also if you go through the indexes on the site - at http://www.yananow.net/Experiences.html you will find many men on ADT some of whom are on intermittent therapy.

All the best

Terry in Australia

Re: Intermittent HT

Hi Jo. I too am on IHT. Currently I am trying a cycle of three months on and three months ff treatment. I was diagnosed with PCa with a PSA of 25.7 and bone mets. Initially I was on Zoladex for 8 months, to a PSA low of 1.91, then came off, hoping for 6 months or more free of treatment. But my PSA rose to 10.7 within 4 months, just before we were due to go away for 3 weeks. After discussion with my oncologist, given I didn't at all like the killing tiredness side-effect of Zoladex, I started on Flutamide instead, which brought the PSA down to 3.46 in 3 months. PSA then rose to 21.2 in just 8 weeks, unfortunately. So I'm now on Flutamide plus Avodart for three months. After 4 weeks PSA was 4.77, and I've just had a blood test, results in a few days time. I'll stay on Avodart when I come off Flutamide mid-December, hoping that the PSA won't rise to more than about 15 in the following three months. It is early days for me (nearly two years from diagnosis though!) and we'll have to wait and see if IHT will work well for me.

My reasons for trying IHT were initially because of some evidence that it can prolong the time to becoming hormone refractory, plus very good evidence that it has no worse survival value than continuous HT. An urology professor who spoke at our support group this week said he believed that anyone on hormone treatment should us it intermittently. For me a strong secondary reason now is that one can be free of side-effects in the off periods, and that certainly includes return of libido!

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