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Patrick the term merely means that the nerves surrounding the maligant cancer cells have also been invaded by the cancer. But the good news is that PCa does not spread via neural (nerve) pathways.
Patrick, it's important to remember that PNI found on biopsy BEFORE an operation is quite different to PNI found AFTER the prostate has been removed.
When you are diagnosed, if PNI is noted it makes the surgeon suspiscious that MAYBE, but only MAYBE, the cancer has gone out of the capsule. In your case, the patholgy shows that there was no spread outside. They know this because they have the whole gland in front of them, which of course is the great advantage of surgery. Yes, they can see there was some involvement of the cancer in the nerves of the prostate, but that involvement was contained within the gland.
I am not a doctor, but I had a robotic with good post op pathology, which also mentioned PNI. I am told that some pathologists do not even bother to record PNI when found AFTER surgery.
