Prostate Cancer Survivors

 

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Re: PSA "Bump" Response

Jack I am not arguing if you are 'right' or 'wrong'. There is no definitive agreement on this aspect of this complex disease. But please read carefully what I said to Steve. I'll repeat it again here, slightly edited for clairty:

Were you given any specific reason for the suggested delay in starting ADT? The only thing I can think of is that your doctor might be thinking that what you are seeing is a radiation "bump" which sometimes occurs about two years after radiation therapy is concluded. ...You might like to ask him this and then weigh up the probabilities/consequences of your options.

I didn't know why the doctor suggested that the rise was not important: I had no access to Steve's medical data: I was saying that he should clarify the question with the man with the qualifications who suggested the delay.

Turns out that the delay was being suggested to delay the 'inevitable onset' of hormone refractory disease.

I do not accept that all disease becomes hormone refractory although there is no doubt that some does.

I have an open mind on the subject of whether PSA, a non prostate cancer specific test always truly reflects that it is only prostate cancer that triggers small increments in test results after surgery plus radiation. There may well be other causes that are not clear because there are no studies that look at this specifically, but that is by the by and I won't argue the points you raise because that was not the point of my post, which was for Steve to discuss with his doctor what his doctor's thinking was.

Hope that's clear now?

All the best
Terry in Australia

Re: PSA "Bump" Response

Jack,
After having my prostate out I was shuffled over to a radiation oncologist who gave me the standard radiation treatment. He told be to expect a bounce at between 1 to 2 years from the prostate cancer cells going through their final death throes. He expected my PSA to go up from .01 to about .1 during the bounce. If it keeps going up then it is not a bounce but recurrence.

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