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Re: PCA-3 test better than PSA

http://www.ncbi.nlm.nih.gov

I would like to respectfully disagree with you regarding PCA-3 and the independent studies. The studies at the website above is what doctors use for their research.

Fred

Re: PCA-3 test better than PSA

There are two basic issues that make PCA-3 unreliable:

1. The original studies required "vigorous massage" of the prostate gland. This is a non-scientific description of procedure. It is not only difficult to interpret - just what is 'vigorous' - but may also be difficult in practice to achieve consistency. Prostate glnads are different sizes as are the fingers of doctors.

2. Part of the calculation of the value of PCA-3 tests invovles the PSA values. Given their inconsistency and variability, such attributes are incorporated in the PCA-3 tests.

Terry in Australia

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